Hello everyone ，I am a BME graduate student .

I just started using DS and  I have some questions that I want to consult.

1. How should I handle the Invalid Residues to apply forcefield  (molecular dynamics) ???

    (1) Will it make a big difference if I delete the Invalid Residues？

    (2) Where do I look up their parameters？

2.How should I set the ligand residue????

   I put the ligand in Tumor necrosis factor alpha to make Molecular docking. 

   But I can't combine ligands into residues(like the ligand in 1SEM), so I can't apply forcefields.

I use SETUNA to take screenshots and it is very convenient. I want to share it with you.

Thank you for any kind of watch and help .