Notebook users trying to use ChemDraw 25 to draw chemical structures might find that it is not working as expected, especially when their Notebook version is 2025. 

Our Developer says that "the user must install ChemDraw_Applications_25.0.2.exe and not ChemDraw_25.0.2.exe in order to get both the 32-bit and 64-bit versions installed which is required for it to work with the Desktop Connector Client in Notebook".

Note that ChemDraw 25 will be officially supported in Notebook version 2026. It works partially with current/older Notebook versions but it is not fully supported in older versions (2025 or earlier).