I have this simple frame

When I run Edit Joints to refresh a static test I get this Error Dialog

What is the significance of this message?  I have checked the beams until I am blue in the face, the model meshes without problems, and test run without problems.  Some of the beams are not on the neutral (I presume this means central) axis, but that should not cause problems.

Can I just ignore this Dialog?  Is its appearance and indication that I should not rely on the test results?