Search path settings won't save?

Don't know if anyone has ever seen this problem but here goes.  One of our machines is having problems storing SolidWorks system options.  Specifically search path locations.  No matter how many times we add new search paths under file locations, it will not maintain those locations.  As soon as you close out of the options dialogue box, those locations are immediately gone.  Any thoughts or ideas would be greatly appreciated.

SolidworksGeneral