Method for moving multiple SW installations on the same machine

My work laptop is starting to feel the crunch, with four discreet SW installations (16-19) on the primary drive (SSD). I'm starting to get squawked at because it's filling up.

I'm working on moving other programs to my rotating secondary drive (2TB) but I need to be careful about handling SW because of... touchy... it can be sometimes.

I guess the easiest way is to completely blow all the installs away and start over. If I go this route is there a guide on how to get four installations to play nicely on the same machine... NOT on the system hard drive?

To forestall the question, I do outsourced design work and many of my customers use old versions and want native file formats.

SolidworksGeneral