Error with microsoft.net assembly registration error

Once I download and install both 2009 SP 4.1 and 2010 PR1, I get an a microsoft.net assembly registration error window pop up.  If I choose send no report and continue with the download and launch Solidworks, I get a window stating Solidworks has encountered an error and must shut down.  Any suggestions to successfully register and use the software?  I have personally never seen this.

Chris

SolidworksAdministration