Determining Energy Loss in flow simulation

Hello, guys.

I'm trying to make a flow simulation in a certain pipe.

I want to define its energy loss generated by my pipe.

as far I know, I have to use the Bernoulli's equation and compare the energy between inlet and outlet.

{v^2 \\over 2}+gz+{p\\over\\rho}=\\text{constant}

The energy can be defined by find the velocity (v), pressure (p), and height (z).

And here's my problem.

I want to make my pipe a little bit different by change it size into a rectangle one.

My questions is, how do I define v, p, and z?

Should I define the mean pressure of inlet and outlet surface?

or maybe I should define it using "point". Take the pressure value at the center point of the rectangle, and so on?

or there is other method? which one is common?

SolidworksFlow Simulation