Is it possible to lock a configuration from ever changing?

Ill give a simple example.  I have a board, this board has different cutouts, of varying sizes and locations.  Therefore I have different configurations, with cuts suppressed/unsuppressed.  The location and size dims modified for the ones that are turned on.

Once I have it like I need, I want that configuration locked.  It seems everytime I make a new configuration.  Sometime, somewhere, somehow I forget to check the "this configuration only" box.  Then I have to go through all the configs, see which ones are AFU and fix them.  As the file grows, this becomes impractical.  Any ideas?