The constraints at the Layout level do not include path-mate, however, if you "Make Part from Block", then at the assembly level, you can constrain a part to a path, but I have found that I have to delete the "Layout:Part-Block fixed" constraint (otherwise SW complains). This really defeats the purpose; essentially I'm trying to leverage the ease of working with sketches and the constraints you can develope in the Layout environment, and then ADD to this by going to the next level higher, the assembly. I'm guessing that SW requires you to break the Layout link mentioned above because it can't ADD the two constraint systems.

There are so many ways to do things I thought I post this to see if anyone has devised a work around.