Should a Manufacturing Product to be picked up be in the same Manufacturing cell as the resource picking it ?

Hello and good morning/afternoon/evening to members of this community,

 

Should a Manufacturing Product created using either synchronize with planning or with manual creation always be in the same manufacturing cell as the resource (robot/conveyor/gantry) picking it ? - see image 1

 Or can the Manufacturing Product be in a completely different manufacturing cell, even if the manufacturing cells are nested ? - see image 2

Wanted to know what the recommended best practice is. 
Regards,
Omar