SMIRKS for metabolic transformations

Does anyone have available SMIRKS for common metabolic transformations in mouse, rat, dog, and

human for the purpose of generating the transformed molecules from a set of input structures? 

If there are literature references with (hopefully) supplementary materials i.e., tables of SMIRKS,

that would be very helpful.

Thank you.

Regards,

Jim Metz

James.Metz@AbbVie.com