Hi there,
Please find attached a sub-protocol for doing simulated annealing using Pipeline Pilot and the Forcite components in the Materials Studio Collection. You can choose the number of cycles, ramps per cycle etc and define whether you want the final frame from the trajectory (ie you are using the simulated annealing to perturb an amorphous cell) or you can pick the N lowest energy frames from the trajectory.
Hope this helps in building out your workflows.
Cheers
Stephen