Flory-Huggins Interaction Parameter for small molecule encapsulation

Hello everyone,

I started working with Materials Studio 7 a few weeks ago. Recently I met following problem:

How do I calculate the Flory-Huggins Interaction Parameter for encapsulated small molecules (encapsulation in different polymers).

I would like to find some clues of the loading capacity by studying the differences in the chi values.

Does anybody have some  "tutorials" or literature?

I would be thankful for hints on general literature, too.

Thank you.

Greetings

Romans