Building nanocluster from an amorphous cell

Dear all,

I want to build some spherical nanoclusters of a polymer with different diameters ranging from 1 nm to 10 nm. can I use a relatively small cell to build large nanoclusters?  in other words, what is the difference between the clusters of the same diameter built from small and large amorphous cells?

Thank you in advance.

Regards,

Farzin