Hi

I am working with Standard Dynamics Cascade for a macromolecule and small molecule complex.  First step of creating this complex has been done. Thanks a lot Jodi.

Submitted a job with all the default protocol parameters.  Just after few minutes job was completed.

When the output molecule is opened, the small molecule looks as is, but, the macromolecule (15 Ang in its active site) looks some thing like a zig zag highly disturbed network chemical structure with no chemical meaning.

Can you guide me to get the expected results from the steps of minimization and dynamics on the complex (macromolecule and small molecule).

Look forward to your help.

Sunil