PURPOSE: Replace residues in a input protein with alternate amino types. This protocol is similar to the DS Build Mutant protocol however no refinement is performed on the protein after the residue(s) is replaced. The protocol contains a DiscoveryScript (Perl on Server) component that does the modifications to the molecule.

USAGE: This protocol can be launched from both the Discovery Studio and Pipeline Pilot clients. To install in Discovery Studio only, go to the Protocol Explorer, right-click over the folder you want to add the protocol to, choose Import, navigate to the location of the Mutate Amino Acids.xml file and enter it as the File Name.

REQUIREMENTS: Discovery Studio Embedded Collection

KEYWORDS: mutate, residue replace

DISCLAIMER: This custom protocol is compatible with Discovery Studio 2.1 and Pipeline Pilot Server versions 6.1.6 and 7.0.1 (SES). It is provided "as is" and is NOT supported by Accelrys nor is it warranted for any purpose whatsoever. The user assumes responsibility for any malfunctions or bugs.