Has anyone successfully run protocols of DS 2.5/3.5 on Win 8 of 64 bit?

Recently I encountered a problem that the task cannot finish and the status of progress remains unchangedly at 0 % once the protocol start. Is it a compatibility issue with Win 8 of 64 bit? Has anybody encountered the same problem and figure it out?

If possible, please tell me how to deal with it...

Thank you so much!