This article describes about the novel classification system for enzymes that is based on sequence based descriptors and pharmacophore mapping which is done with Discovery Studio pacakge. The full article citation is given below and can be downlaoded at
http://dx.doi.org/10.1016/j.biotechadv.2010.09.003
Udatha, D.B.R.K.G.; Kouskoumvekaki, I.; Olsson, L; Panagiotou, G. The interplay of descriptor-based computational analysis with pharmacophore modeling builds the basis for a novel classification scheme for feruloyl esterases. Biotechnol Adv 2011; 29(1):94-110.