Hello Accelyrs Community,

We are modeling carbohydrates using the CHARMm forcefield through the Discovery Studio 3.5 Client platform. There have been extensions to the CHARMm forcefield that more accurately model carbohydrates (the Carbohydrate Solution Force Field (CSFF) presented here http://pubs.acs.org/doi/abs/10.1021/ja036959e) and we wish to incorporate these modifications into our modeling. Is there a way to add this forcefield or incorporate the alterations into the existing forcefield in the CHARMm forcefield in DS platform or do we need to install the stand alone CHARMm forcefield to be able to modify it?

Thank you,

David