Just wanted to put this out there...

I have been struggling with intermittent loss of functionality of hotkeys, drag and drop, as well as the use of my Windows key for months.  I finally ran across a forum post somewhere else that pointed to a text replacement application called Texter put out by Lifehacker.com.  I used this program (it is really handy), however once I removed it and rebooted those problems were gone and have not come back.  Just wanted to put this info on the forum in case anyone runs into the same issues.