MODSIM 3DXCONFERENCE Modeling_and_Simulation_from_an_Industry_Perspective
I am pleased to invite you to hear my presentation on the Global 3DEXPERIENCE Modeling & Simulation Virtual Conference, on November 17.
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Computational heart modeling is a valuable tool to simulate heart hemodynamic behavior and to evaluate medical devices such as leadless pacemakers. The Living Heart Human Model (LHHM) is a commercial, four chamber heart model in which the dynamic behavior is regulated by physically realistic mechanical, electrical and fluid physics. The LHHM model outputs detailed stroke volume, blood pressure and timings information during cardiac cycles. LHHM can also accurately simulate the hemodynamic performance of the heart during exercises for heart rates ranging from 90-160 beat/min. For a paced heart, heart rate changes are not controlled by autonomic nerve intervention, and often are not associated with excise and changes in body oxygen requirements. As a result, the hemodynamic behaviors of the heart would be different for a paced heart from that of a heart during exercise. Furthermore, the amount of pre-programed AV delay also has large impacts on the hemodynamic behaviors of a heart during pacing. The objective of this study is to quantitatively measure the differences in hemodynamic behavior between paced and exercised hearts using LHHM, and to study the effects of AV delay on cardiac performance. This study demonstrates how simulation can provide additional clinical insight into the relationship between heart rate and physiological characteristics such as contractility, body resistance etc.
Presentation Replay
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Staff Engineer
Abbott Labs
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