PAINS Map & Filter

Just shared a PAINS Map & Filter component on the Protocol Exchange on ScienceCloud.

https://exchange.sciencecloud.com/exchange/browse#details:371/PAINS%20Map%20&%20Filter

Wikipedia: Pan-assay interference compounds (PAINS) are chemical compounds that often give false positive results in high-throughput screens. PAINS tend to react nonspecifically with numerous biological targets rather than specifically affecting one desired target.[2] A number of disruptive functional groups are shared by many PAINS.

https://en.wikipedia.org/wiki/Pan-assay_interference_compounds

 

Thanks @MH for the original protocol, and @MS for the advice :)

chemistry collection