PURPOSE: The following script can be used to measure the nucleic acid helical parameters. It assumes that the helix axis coincides with the Z axis of the coordinate space. This is true for structures built using the Nucleic Acid builder in Discovery Studio but will likely not be true for structures from other sources. The parameters reported are Rise, Twist, X-displacement, Propeller Twist, Inclination and Roll.

Definitions as found in https://www.intechopen.com/chapters/16928

INSTALLATION: Save MeasureNucleotideParameters.pl to a local directory or location accessible from the Files Explorer

USAGE: From the DS Client: From the Files Explorer, right-click on the MeasureNucleotideParameters.pl file and select Open With | Script Window then launch the script using the Run command from the Scripting toolbar. The output parameters are written to the Output portion of the Script Window.

DISCLAIMER: This custom script is compatible with Discovery Studio 2022. The code or software provided by Dassault Systemes Biovia Corp. ("BIOVIA") in conjunction with this request is provided under the same license terms and restrictions as the underlying BIOVIA software it is intended to be used with, including license duration and location based restrictions, with the following exceptions. This software is provided on an AS-IS and AS-AVAILABLE basis with no guarantee or warranty, and is not subject to maintenance, updates, or support. When your license to use the underlying BIOVIA software terminates, your license to use this software will also terminate. BIOVIA makes no warranty that this software will be usable for any purpose.​​​​​​​